Santa Rosa de Viterbo (1233-1251) donned the simple drab cloak of the Franciscans at an early age, but the interior of the church built in her honor in Queretaro in 1752 is gilded to the hilt. Fresh flowers cover the altar, fitting as Santa Rosa de Viterbo is the patron saint of flower growers and florists. The massive scroll buttresses attached to the façade are decorative, not functional, and are believed unique to this baroque church.
The adjacent convent was closed by the Reform Laws of 1861, and today serves as a center for the study of design and graphic arts.